Plant in full sun to light shade in a well-draining soil. Hardy to 10° F. The selection we have is a graceful smaller growing plant with gray leaves that have only tiny marginal spines.

The neotype for this species is noted as from between Laredo and Catarina in Texas but an occurrence of a native planting is no longer known although there are many variants found as cultivated plants in arid areas of north-central and northeastern Mexico and South Texas. It was described in 1901 in the Bulletin du Muséum d'histoire Naturelle by the French botanist Jules Poisson (1833-1919) who attributed the name to another French botanist Jean Francois Cels (1810–1888) based on a specimen collected in Mexico that was then growing in Paris. The name for the genus is one given by Swedish naturalist Carolus Linnaeus. It comes from the Greek word 'agaue' (agauos or agavos) meaning "noble" or "splendid" and originates from Greek mythology. Agaue was the daughter of Cadmus, the king and founder of the city of Thebes, and of the goddess Harmonia. The name was first used by Linnaeus in 1753 when he described Agave americana. The specific epithet honors the French surgeon and botanist Frederic Albert Constantin Weber who in 1902 described Agave tequilana.

Howard Scott Gentry noted in his landmark Agaves of Continental North America that he had observed a great variation within the species with some forms green while others are glaucus gray and usually small teeth or denticles are present to an indeterminate extent on gracefully arching leaves. We grew this form with small teeth from 2005 until 2011 from plants originally received from Rancho Soledad nursery in 2003. We also received from them and continue to grow Agave weberi 'Reiner's Selection'. 

The information about Agave weberi displayed on this web page is based on our research conducted in the nursery's horticultural library and from reliable online resources. We also include observations made about it as it grows in our nursery gardens and other gardens we have visited, as well how the crops have performed in containers in our nursery field. We will also incorporate comments we receive from others and welcome hearing from anyone with additional information, particularly if they can share cultural information that would aid others in growing this plant.